Ahh... Reads differently. :wink:
Seriously, I think the Japanese shaft drives are typically good for the life of the bike. I don't know about Moto Guzzi, but I do know that the BMWs fail. They are a totally different design. Handle a little better, wear a lot worse, require more maintenance (annual spline lubing) - and yes, a buddy of mine had his replaced to the tune of about $2000. That was on a K75 at fairly high mileage (75K or 80K I think).
A chain and sprockets have a limited lifespan no matter what you do. Replacement will come at intervals of 12,000 to 18,000 miles typically depending on usage and care. They need frequent lubing, occasional cleaning, and periodic adjustment - all stuff I didn't have to deal with for 20+ years - and didn't miss. Chains do transmit power a more efficiently. They are lighter. You can alter drive ratio with different sprockets. They have a more neutral effect on handling. I know all that, but I still prefer the maintenance free aspect of shaft drive.
And yes, I've read of one incident where a chain broke on a DL1000 and trashed the engine case in the process. They also tend to gunk up the clutch servo which sits right behind the chain, causing eventual contamination or even loss of clutch fluid.
For me it boiled down to having to accept chain drive as part of the package. I love the way my V-Strom performs. There wasn't a non-chain drive bike in the price range that I liked as well. After 40 years of riding, I can say there are no perfect bikes. Just some very good ones. And the V-Strom is very enjoyable to ride.