I would test an inconspicuous spot on the fender with a very mild solvent like 90% rubbing alcohol (isopropyl alcohol.) If it doesn't change the finish on the good part, then I would try it on the stained part with a cotton swab. Again, just a tiny area to see how it reacts. If both those tests go well, then I would clean the whole fender with it.
If it doesn't pass those two tests, then I would do the same thing with plastic safe car "wax" like Turtle Wax Ice. It's designed to work well on paint, plastic and rubber:
Good luck and keep us posted!
If it doesn't pass those two tests, then I would do the same thing with plastic safe car "wax" like Turtle Wax Ice. It's designed to work well on paint, plastic and rubber:

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Good luck and keep us posted!