Excellent! All kinds of nuggets and tidbits came out in this thread.
15-18% of people in N. America are allergic to nickel. It is a very common cause of contact dermatitis. Some sources claim that it's 5x more common in women than among men. This is not true, it's just drastically underdiagnosed in men.
Nickel is a common alloy in inexpensive jewelry, especially ear rings. More women than men wear inexpensive jewelry and ear rings and are more likely to be diagnosed. Allergies to chromium are also fairly common.
As an optometrist, I deal with spectacles every day for decades. Men and women have similar or equal need for spectacles, and nickel allergy is a 50/50 deal with respect to gender. Nickel is a very common part of the alloy for most metal frames because it's cheap, pretty strong, plates well, easily formed, alloys with almost any metal, etc. If your glasses make you break out along your temples or ears, it's contact dermatitis from the nickel in the frame. Switching to titanium or plastic frames solves that.
Nickel allergies are common in 10 percent of the population in the United States and 18 percent of people in North America, including 11 million children.
www.medicinenet.com
Trivalent zinc chromate turned out to be an interesting rabbit hole. The plating industry (especially automotive) switched to this to reduce or eliminate the use of hexavalent chromium, which is some seriously bad shit. Ask Pacific Gas and Electric about that.
The Jaguar people think about this problem a lot and recommend not using anti-seize compound on spark plugs (in aluminum heads) that have anticorrosion plating already. They say it's because it easily leads to overtightening, which leads to stripping and breaking and other bad things. They further claim that the plugs with trivalent plating prevent problems on removal because the plating fractures off the plug before the threads strip, or the spark plug breaks. I am dubious that that's the real explanation. It does prevent rust, which can weld a spark plug right into the head. And the zinc probably acts as the sacrificial component of all the metals in the system.