I would avoid Easton and Stroudsburg - they're not big cities, but you'll hit lots of lights and traffic.
There's not really a good way to get accross the Lehigh Valley without some slab a/o traffic, stoplight-to-stoplight. ... that I've found, anyway.
Leaving Q town, 212/ 412 are more scenic than 313/ 563 - which are relatively flat, straight roads.
Between Easton and Stroudsburg, in the area bounded by Rt 33 to the West, the Delaware River to the East, I don't think there IS a bad road. Very farmy. Hilly next to the river. On the Jersey side hugging the Delaware is a nice trip, too.
I enjoy 191 North of Stroudsburg. Again, in the area between Stroudsburg, the Delaware River, Wilkes-Barre/ Scranton, and the NY line is very pretty. I don't think there are any "bad" roads there as long as you avoid the highways and cities.
Have fun, ride safe.