I take dirt bikes to Colorado almost every summer. I usually do have more problems then my bike at altitude. But I re-jet my KTM 525EXC for the about 10,000 feet, so it runs REALLY good. I know what to expect, now that I've been that high a few times and your right my body doesn't like it. I just want to make sure the V-Strom's fuel injection will compensate at altitude, otherwise it may have some issues with the passes and Pike's Peak.
The only place I can think of that I will be at 14,000 feet is if I ride up to the top of Pikes Peak on my V-Strom, which is something I've wanted to do. There's also a few passes around 12,000 feet that I will be going over on the V-strom. I will probably be loaded down with luggage, so it will be working and needs to be running right.