The only thing that has come loose on my V-Strom is the chain guard, and that is apparently quite common. Use some blue loctite there, and maybe the front guard.
Unless you have some good reason to doubt a particular area, just go over the bike twisting anything you can see by hand. Anything that is loose will become apparent. Some have reported issues with the fuel tank fasteners, but generally things falling off during a ride is unusual.
It is not a good practice to repeatedly re-tighten bolts as anything tightened correctly may then become stretched and fail.
BTW I once took a 7 day trip with friends and they invited along a friend riding a HD Sporty. Now there's a bike in need of Loctite. He had an indicator fall off and hang by the wire, problems with the headlight and instrument area bolts, the seat, and the battery box coming loose and almost dropping out. On the 3rd day I needed to duct tape a lump of truck tyre rubber that I found by the side of the road onto the 3/4" rod from which an HD rubber footrest had slid off, bouncing down the road and over a fence. We never did find it, and so I rigged up a replacement. Those HD's used a sort of handlebar grip as a footrest rubber, just like Brit bikes used to have (and 1960's Japanese bikes).
In the end he was asking them not to say anything to me about the tools quietly coming out at the end of each day.
Just go over your bike - particularly after the first day. As well as basic tools (mostly the OEM toolkit) and a Leatherman tool I also carry a puncture repair kit, a mini plug in pump, duct tape, zip ties, and tie wire. I run a Tutoro oiler which does away with the need to carry chain lube.